A prospective, multi-center, observational study on the use of interferon beta-1a (Rebif) therapy in Egyptian patients with Multiple Sclerosis

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A prospective, multi-center, observational study on the use of interferon beta-1a (Rebif) therapy in Egyptian patients with Multiple Sclerosis

Objective: The primary objective of this study is to describe the disease characteristics of the cohort of MS patients undergoing Rebif treatment. Design: This is a multicentre, open label, non comparative, non randomized study conducted in Egypt on the use of interferon beta-1a (Rebif) therapy in Egyptian patients with relapsing multiple sclerosis according to McDonald criteria. Subjects: Egyp...

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The efficacy and safety of first-line disease-modifying therapies (DMT) for relapsing-remitting multiple sclerosis (RRMS) has been demonstrated in pivotal, randomized trials, but these studies do not reflect the routine care setting where treatment gaps or switches are common. The Avonex as Treatment Option for Untreated MS Patients (AXIOM) trial assessed the efficacy of newly-initiated intramu...

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Fingolimod versus High Dose Interferon Beta-1a in Multiple Sclerosis: A Randomized Clinical Trial

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Antibodies to Interferon beta in Patients with Multiple Sclerosis Receiving CinnoVex, Rebif, and Betaferon

Treatment with interferon beta (IFN-β) induces the production of binding antibodies (BAbs) and neutralizing antibodies (NAbs) in patients with multiple sclerosis (MS). NAbs against IFN-β are associated with a loss of IFN-β bioactivity and decreased clinical efficacy of the drug. The objective of this study was to evaluate the incidence and the prevalence of binding antibodies (BAbs) and neutral...

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ژورنال

عنوان ژورنال: The Egyptian Journal of Hospital Medicine

سال: 2013

ISSN: 2090-7125

DOI: 10.21608/ejhm.2013.16073